There are over 140 RNA modifications (aka epitranscriptome), most of which are poorly studied. Our long-term interest is to understand how RNA modifications affect gene regulation and beyond. We currently focus on A-to-I RNA editing where genomically encoded adenosine is changed to inosine (recognized as guanosine) in the RNA. We aim to identify RNA editing events in the entire transcriptomes, and understand their regulation and functions. Our approaches include molecular genetics, genomics, computational biology, and technology development.

We are actively in search of motivated talents (postdocs, graduate students, and undergraduate students) to join us for our adventure.

logo somlogo genlogo